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Error Code 643 is common for all the Windows Operating systems when you try to install the windows updates. It usually appears when Windows 11 or Windows 10 or Windows 7 update system is broken or if there is any network related glitches.
Usual causes for this windows update error code 643 are communication failure over the internet with Microsoft update servers.
Firstly, I will suggest you to do Windows Troubleshoot for Error Code 643. Later, Disable the proxy internet connection and try again to install the windows update.