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Mixing Duratia with certain prescription medications can also lead to adverse effects. Due to its mechanism of action and metabolism, Duratia may interact with other medications, particularly those that affect serotonin levels or are metabolized by the same liver enzymes. These interactions can result in an increased risk of side effects and may impact the effectiveness of both substances. It is crucial for individuals to consult their healthcare provider before combining Duratia with any other prescription medication.